VOLUME 37 | ISSUE 4 | JULY-AUGUST 2017

Original Article Font size: Decrease font Enlarge font

Utilization and adherence to guideline-recommended lipid-lowering therapy at an academic medical center

Khalid A. Alburikan, Rayah M. Asiri, Abduallah M. Alhammad, Amer A. Abuelizz, Ghada A. Bawazeer, Mohammed H. Aljawadi

From the College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

How to cite this article:

Alburikan KA, Asiri RM, Alhammad AM, Abuelizz AA, Bawazeer GA, Aljawadi MH. Utilization and adherence to guideline-recommended lipid-lowering therapy at an academic medical center. Ann Saudi Med 2017; 37(4): 276-281.

DOI: 10.5144/0256-4947.2017.276

Abstract

BACKGROUND: Clinical guidelines for managing blood cholesterol were updated in November 2013. 

 

OBJECTIVE: To evaluate the adherence to the 2013 American College of Cardiology/American Heart Association (ACC/AHA) guideline recommendations for statin therapy in the treatment of elevated blood cholesterol in high-risk patients.

 

DESIGN: A single-center, retrospective, observational study.

 

SETTING: A tertiary care academic medical center in Riyadh, Saudi Arabia.

 

PATIENTS: Consecutive adult patients discharged with a prescription for any of the statin medications group between 1 June 2015 and 31 December 2015.

 

MAIN OUTCOME MEASURE(S): Adherence to the 2013 ACC/AHA guidelines for management of cholesterol by statin therapy in high-risk patients.

 

RESULTS: Of 1094 patients, 753 (68.8%) met the inclusion criteria of the study. Of these 753 patients, 53.5% had atherosclerotic cardiovascular diseases; 29.2% had diabetes; 0.9% had an LDL-C level >190 mg/dL; 10.8% had an estimated 10-year risk >7.5%; and 4.9% had no risk. Two hundred and eight (27.6%) patients received statin therapy at an inappropriate intensity according to their risk group based on the guideline; 126 (16.7%) received less than the ideal intensity.

 

CONCLUSION: Approximately one-third of patients received statin therapy at an inappropriate intensity according to the guideline recommendation. Wide application of the 2013 ACC/AHA cholesterol guidelines in our practice would optimize the utilization of statin therapy at the ideal intensity in high-risk patients. 

 

LIMITATION: Drug-drug interactions and intolerance to statin therapy were not considered when we evaluated adherence among high-risk patients. 

 

 

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