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Manuscripts are received with the understanding that they are original and have not been published (in print or online) or are not under simultaneous consideration by another publication. If an abstract of the work has been previously published or if manuscripts using the same database or relating to the same topic have been published or submitted by any of the authors, this should be disclosed. An abstract published prior to a full report is not regarded as a duplicate publication. Previous publication in another language does not preclude publication in the Annals, but it should be disclosed and permission obtained from the other publisher. Authors who violate these requirements will be subject to an extended publication ban. Accepted manuscripts may not be published elsewhere without the Annals’ permission. We only accept manuscripts submitted online at See the Checklist for authors available on the ScholarOne site and on for more information on submitting your manuscript. Careful attention to instructions will ensure that initial submission is successful. If you have difficulty, contact us by e-mail at




In the interest of reader confidence in data presented in the Annals, we now require that datasets used in the study be submitted with the manuscript on initial submission. Any of the common file formats are acceptable (csv, xls, xlsx, sav (SPSS), dta (SAS), but not GraphPad prism, which should be converted to a common file format). If necessary, please include an English translation for variable names in the dataset. 

We like to check the summary statistics and other values for all papers we publish, and might recommend changes to figures and tables. It is for our internal use only and will not be available to others, including reviewers. If you are concerned about data anonymization, you can take measures to anonymize the data (see: Annals of Saudi Medicine must review the dataset and scrutinize the statistical aspect of the submitted work prior to publication. Refusal to comply with this policy will lead to withdrawal of acceptance for publication. 




The format of the Annals of Saudi Medicine, complies with “Uniform Requirements for Manuscripts Submitted to Biomedical Journals” published by the International Committee of Medical Journal Editors (see We encourage the use of reporting guidelines such the CONSORT statement for randomized, controlled trials and the STROBE statement for observational studies (see For human gene nomenclature, consult the recommendations page of the Human Genome Variation Society at Manuscripts, including tables, references, and figure legends, must be prepared using a word processing program. Before submitting a manuscript, create an account on the ScholarOne Manuscripts website. When you submit the manuscript online, a current email address must be provided for all authors. The number of authors should be limited to four on brief reports, case reports, and letters. The Annals of Saudi Medicine follows the International Committee of Medical Journal Editors in defining the role of authors and contributors (please visit


ABSTRACT: All original articles and brief reports must contain a structured abstract of not more than 350 words. Usually, the abstract should be divided into: Background, Objectives, Design, Setting, Patients (or Subjects) and Methods, Main Outcome Measures, Results, Conclusion, and Limitations. The subheadings should not be combined.



MANUSCRIPT FORMAT: Most original articles have the following format: Introduction (the question the paper intends to answer, what remains unknown, how patients could benefit from the answer); Patients and Methods (study design and methods, operational definitions of major variables, description of the patient or subject population, and laboratory and statistical methods); Results (pertinent findings in a logical sequence with tables and figures as necessary); and Discussion (conclusions based on the findings, evidence from the literature that supports the conclusions, conflicting evidence, applicability of the conclusions, limitations of the study, and implications for future research or clinical applications). Statistics should be described in enough detail to enable a knowledgeable reader, with access to the original data, to verify the reported results.


REFERENCES: List references in consecutive numerical order (the order of citation in the manuscript, and not alphabetically). Once a reference is cited, all subsequent citations should be to the original number. All references must be cited in the text or tables. References to journal articles should be formatted in the style recommended by the National Library of Medicine ( References to material on the Internet should include the date of access. Manuscripts with incorrectly formatted citations will be returned to the author for correction. The author is responsible for the accuracy and completeness of the references and for their correct textual citation. In-text reference numbers should be superscripted and placed after the period (not in parentheses), as at the end of this sentence.1


UNITS OF MEASUREMENTS: With the exception of blood pressure, all units of measurement and laboratory values must be expressed in SI units; conventional units may be included parenthetically. The international nonproprietary name should be used for drugs with mention of the trade name on first mention. Authors should consult recent issues of the Annals for examples of appropriate style and format.


ILLUSTRATIONS: Photographs, scientific graphs, and other illustrations should be uploaded as separate files, not embedded in Microsoft Word. The format should be .TIF or .EPS at 300 dpi (dots per inch) or greater resolution (please see File saving options can be found in most software in the ‘Save As’ or ‘Export’ commands under the ‘File’ menu. Save original files in the event that submitted files are not suitable for publication. Graphs must be digitally scanned, if not prepared initially as an electronic file in a scientific graphing program. Simple line and bar charts are usually sufficient. Do not use 3D charts unless the 3rd dimension presents data. The resolution of images prepared in Microsoft PowerPoint (72 dpi) is not usually sufficient for print publication (minimum 300 dpi). Subjects in pictures should not be identifiable. Written permission must accompany any illustration that has been previously published. All illustrations must be numbered as cited in the text in consecutive numeric order. For photomicrographs, the legend should include the original magnification and stain used.


Tables. Tables should be prepared using the table function in Microsoft Word or other software. Verify tabular statistics to make sure they tally and match data cited in the text. 






EQUATOR ( the QUAlity of Trials and Other Research). The EQUATOR Network seeks to improve the quality of scientific publications by promoting transparent and accurate reporting of health research. The EQUATOR site has links to the following guidelines as well as others.






STROBE (STrengthening the Reporting of OBservational studies in Epidemiology) is an international, collaborative initiative of epidemiologists, methodologists, statisticians, researchers and editors involved in the conduct and dissemination of observational studies.


The TREND statement was specifically developed to guide standardized reporting of nonrandomized controlled trials. The TREND statement complements the widely adopted CONsolidated Standards Of Reporting Trials (CONSORT) statement developed for randomized controlled trials. A collective effort in promoting transparent reporting is valuable to improve research synthesis and advance evidence-based recommendations for best practices and policies. We encourage all researchers, funding agencies, journal editors, and reviewers to use the TREND Statement as a guide when designing evaluation studies, reporting evaluation results, and reviewing manuscripts for scientific publication.





The STARD (Standards for Reporting of Diagnostic Accuracy) initiative aims to improve the accuracy and completeness of reporting of studies of diagnostic accuracy in order to allow readers to assess the potential for bias in a study and to evaluate the generalisability of its results.






Please use the guidelines developed by the Human Gene Organization (HUGO) nomenclature committee for human genes:


Human genes


Use approved gene symbols obtained from the HUGO Nomenclature Committee ( Another useful reference is the AMA Manual of Style, Section 15.6.2 Human Gene Nomenclature (



Human genetic variation


Designation of single nucleotide polymorphisms (SNPs), deletions, insertions, and other gene mutations should follow the guidelines given in Hum Genet 2001; 109:121–124 (



Human cytogenics


Use ISCN nomenclature for cytogenetics notation: Schaffer LG, Slovak ML, Campbell LJ. ISCN 2009: An International System for Human Cytogenetic Nomenclature (2009): Recommendations of the International Standing Committee on Human Cytogenetic Nomenclature. S. Karger AG (Switzerland);2009.


Mouse strain and genetic nomenclature: International Committee on Standardised Genetic Nomenclature for Mice ( new symbols and names for genes should be obtained before submission.


Human gene names and loci should be written in uppercase italics and Arabic numerals. Protein products are not italicized.



Adapted from Guidance for Authors on the Preparation and Submission of Manuscripts to Pharmacogenetics and Genomics




The Annals of Saudi Medicine (ASM) welcomes submissions of videos via SchoalrOne Submission System ( in one of two formats.  All videos are subject to peer review by the editorial board and by reviewers in appropriate specialties. The first type is Video Manuscript Submission: the ASM accepts video manuscript submission to accompany submitted Original Articles, Case Reports, Brief Reports, Mini-Review, Special Communication, Editorial, What's Your Diagnosis?, Images in Medicine, Guidelines, or Letter to the Editor. For instance, authors can describe the technical procedure/innovative technique that was used in the article or give more description about their unique work in a simple and understandable presentation. The second type is Technical Notes: authors should submit a manuscript along with the video; the text of the manuscript should not exceed 1,500 words with references and should be subdivided to: Introduction, Technical Method, Discussion, Results, and Conclusion. For example, the submission of videos of innovative laparoscopic procedures or endoscopies that include demanding and highly skillful techniques. For more details, please find the below information: 



1. Language: Videos should be narrated in English

2. Video Format: Only MP4

3. Upload Limit: No longer than 10 minutes

4. Quality: The ASM allows 4K submission, but it is not a compulsory requirement. All submissions must be HD though, maximum to 1080p (Full HD). 

5. Keywords: More than five keywords should be provided to attain search engine optimization.

6. Written Consent: Authors should sign a consent form which indicates that they obtained approval from their institution, university, patients, etc.

7. Other Information: Authors should include: 

7.1. Names of the speakers in the video, 

7.2. Date and place of recording, and

7.3. Short captions. 

8. Other Technical Information (if applicable): 

8.1. Video codec: H.264,

8.2. Video frame rate: 24, 25, 30,

8.3. Video bit rate: 1080p (8 Mbps), 720p (5 Mbps), 480p (2.5 Mbps),

8.4. Aspect Ratio: 16:9,

8.5. Audio codec: AAC-LC,

8.6. Audio channels: Stereo (2.1), 5.1,

8.7. Audio sample rate: 48khz, 96khz, and

8.8. Audio bit rate: Stereo (384 kbps), 5.1 (512 kbps)





We follow the guidelines of the Committee on Publication Ethics ( on duplicate publication, fabricated data, undisclosed conflict of interest, plagiarism, and other issues of publication and scientific misconduct. Authors will be banned from submitting to the Annals in the future and their institutions notified when misconduct is encountered. The Annals of Saudi Medicine also follows the AMA Manual of Style in case of receiving a manuscript from the editorial board members, "editors and editorial board members should refrain from making any decisions or recommendations about manuscripts in which they have a personal, professional, or financial interest. In the event that an editor works alone and has a conflict of interest with a particular manuscript, he or she should assign that manuscript to a guest editor or a member of the editorial board and should not take part in the review and editorial decision of such manuscripts."



The authors are entirely responsible for the accuracy of all statements and data (including drug dosages) contained in the manuscript, the accuracy of all reference information, and for obtaining permission from the author and publisher of any previously published material included in the submitted manuscript. The authors should identify any financial support for the research and state any relationships of authors with commercial entities in an acknowledgment at the end of the manuscript. The corresponding author of accepted manuscripts will receive an edited manuscript for “final author approval.” The author(s) should review this carefully, as they are responsible for all changes, including those made in final editing.




All manuscripts reporting the results of experimental investigation involving human subjects should include a statement confirming that informed consent was obtained from each subject or subject’s guardian, after approval of the experimental protocol by a local human ethics committee.

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